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Influenza, Human

A Clinical Study to Evaluate the Efficacy, Safety and Immunogenicity of an Adjuvanted Influenza Vaccine Compared to a Non-adjuvanted Influenza Vaccine in Adults ≥65 Years of Age
NCT06087640 | PHASE 3 | INTERVENTIONAL

This Phase 3 study is a randomized, observer-blind study of MF59-adjuvanted influenza vaccine (aQIV or aTIV) compared with a non-adjuvanted influenza vaccine (QIV or TIV) in adults ≥65 years of age. The aim of the study is to evaluate MF59-adjuvanted influenza vaccine compared with non-adjuvanted influenza vaccine in the prevention of reverse transcription-polymerase chain reaction (RT-PCR)-confirmed influenza A and/or B in subjects ≥65 years of age.

Trial Information
90 Sites
35800 Participants
Recruiting
65 Years to 65 Years

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Universitair Ziekenhuis Gent
Gent,Belgium
ResearchLink
Linkebeek,Belgium
MHAT Dr. Tota Venkova
Gabrovo,Bulgaria
Medical Center Zdrave
Kozloduy,Bulgaria
Medical Centre Leo Clinic EOOD
Lovech,Bulgaria
Medical Center Hera EOOD
Montana,Bulgaria
MultiProfile Hospital For Active Treatment Dr. Stamen Iliev AD
Montana,Bulgaria
MC Med Consult Pleven
Pleven,Bulgaria
Ambulatory Outpatient Medical Practice for First Patient Care Zaprin Pepelov
Plovdiv,Bulgaria
Multiprofile Hospital for Active Treatment Sv. Panteleymon Plovdiv
Plovdiv,Bulgaria
Medical Center Prolet EOOD
Ruse,Bulgaria
Specialized Hospital For Active Treatment Of PneumoPhthisiatric Diseases Dr. Dimitar GramatikovRuse EOOD
Ruse,Bulgaria
Diagnostic Consultative Center Sevlievo EOOD
Sevlievo,Bulgaria
DCC Sliven
Sliven,Bulgaria
DCC Sofia
Sofia,Bulgaria
Medical Center Hera Pulmonology Office
Sofia,Bulgaria
Medical Center Intermedica
Sofia,Bulgaria
Medical Center Excelsior OOD
Sofia,Bulgaria
AIPPMP Dr Zhaneta Demireva
Stamboliyski,Bulgaria
CCR Brno s.r.o.
Brno,Czechia
MUDr. Jakub Strincl, s.r.o.
Liberec,Czechia
CCR Ostrava, s.r.o.
Ostrava,Czechia
Zdravi fit, s.r.o.
Protivín,Czechia
Prof. MUDr. Jiri Beran, s.r.o.
České Budějovice,Czechia
ADMED, s.r.o.
České Budějovice,Czechia
Oulu Vaccine Research Clinic
Oulu,Finland
Tampere Vaccine Research Clinic
Tampere,Finland
Turku Vaccine Research Clinic
Turku,Finland
JSC Evex Hospitals
Batumi,Georgia
LTD Hospital Service
Kutaisi,Georgia
Acad. G. Chapidze Emergency Cardiology Center
Tbilisi,Georgia
K. Eristavi National Center of Clinical Surgery
Tbilisi,Georgia
University Hospital Consorziale Policlinico
Bari,Italy
PO A. Manzoni di Lecco, ASST Lecco
Lecco,Italy
Ospedale Fatebenefratelli e Oftalmico, ASST Fatebenefratelli Sacco
Milano,Italy
Korea University Ansan Hospital
Ansan,Korea, Republic of
Inha University Hospital
Incheon,Korea, Republic of
Hallym University Kangnam Sacred Heart Hospital
Seoul,Korea, Republic of
Ajou University Hospital
Suwon,Korea, Republic of
UAB InMedica
Kaunas,Lithuania
JSC Sauls eimos Medicinos Centras
Kaunas,Lithuania
Hospital of Lithuanian University of Health Sciences Kauno klinikos
Kaunas,Lithuania
InlitaJSC Santara CTC
Vilnius,Lithuania
Emotional Brain BV
Almere,Netherlands
Health Index Multispecialty and LyingIn Clinic
Bacoor,Philippines
St. Michael Family Hospital
Bulacan,Philippines
Norzel Medical and Diagnostic Clinic
Cebu,Philippines
CT CARE Group
Dasmariñas,Philippines
Davao Doctors Hospital
Davao City,Philippines
West Visayas State University Medical Center
Iloilo City,Philippines
St Paul's Hospital Iloilo
Iloilo City,Philippines
St Paul's Hospital Iloilo
Iloilo City,Philippines
Philippine General Hospital
Manila,Philippines
Philippine General Hospital
Manila,Philippines
Manila Doctors Hospital
Manila,Philippines
San Juan de Dios Hospital
Pasay,Philippines
Quirino Memorial Medical Center
Quezon City,Philippines
Silang Specialist Medical Center
Silang,Philippines
RCMed Oddzial Sochaczew
Sochaczew,Poland
KOMED Centra Kliniczne Staszow
Staszów,Poland
ETG Warszawa
Warsaw,Poland
FutureMeds Targowek
Warsaw,Poland
FutureMeds Sp. z o.o.
Wrocław,Poland
FutureMeds Lodz
Łódź,Poland
Sana Monitoring
Bucuresti,Romania
Ames Research Center
Călăraşi,Romania
Clintrial Medical Center
Reșca,Romania
NovaClin Medical Research Center
Timişoara,Romania
Josha Research Center
Bloemfontein,South Africa
University of Cape Town Lung Institute
Cape Town,South Africa
TREAD Research
Cape Town,South Africa
Tiervlei Trial Centre
Cape Town,South Africa
Ubuntuclinical Research (Krugersdorp)
Krugersdorp,South Africa
Be Part Research
Paarl,South Africa
Limpopo Clinical Research Initiative
Thabazimbi,South Africa
EAP Vic CAP El Remei
Barcelona,Spain
Hospital Universitario Son Espases
Palma de Mallorca,Spain
Hospital Povisa
Vigo,Spain
Taipei Medical University Shuang Ho Hospital
New Taipei City,Taiwan
China Medical University Hospital
Taichung,Taiwan
National Cheng Kung University Hospital
Tainan,Taiwan
Taipei Medical University Wanfang Hospital
Taipei,Taiwan
Taipei Medical University Taipei Medical University Hospital
Taipei,Taiwan
Hacettepe University Faculty of Medicine
Ankara,Turkey
Akdeniz University Faculty of Medicine
Antalya,Turkey
Dicle Universitesi Tip Fakultesi
Diyarbakır,Turkey
Goztepe Suleyman Yalcin City Hospital
Istanbul,Turkey
Kocaeli University Faculty of Medicine
Kocaeli,Turkey,41380
Karadeniz Technical University Faculty of Medicine
Trabzon,Turkey
Charles River Medical Group, Mutala Trust and Infectious Disease Research Laboratory
Harare,Zimbabwe

Study Eligibility Criteria

Additional Studies

Additional studies can be found at ClinicalTrials.gov