- * Aged ≥ 6 years
- * Documented congenital fibrinogen deficiency: fibrinogen deficiency manifested as afibrinogenemia with plasma fibrinogen activity and antigen at screening undetectable (i.e. \< 20 mg/dL)
- * Informed consent signed by subject or legal guardian
Fibrinogen Deficiency
Human Fibrinogen - Pharmacokinetics
NCT00496262 | PHASE 2 | INTERVENTIONAL
This study evaluated the single-dose pharmacokinetics of human fibrinogen concentrate and clot strength (maximum clot firmness \[MCF\]) in subjects with congenital fibrinogen deficiency. MCF was measured to demonstrate the functional activity of replacement fibrinogen when a fixed dose of human fibrinogen concentrate was administered.
Trial Information
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Aurora,Colorado,United States,80045
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St. Petersburg,Florida,United States,33701
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Chicago,Illinois,United States,60614
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Scarborough,Maine,United States,04074
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New York,New York,United States,10021
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Pittsburgh,Pennsylvania,United States,15232
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Cagliari,Italy,09100
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Firenze,Italy,50134
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Milano,Italy,20122
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Napoli,Italy,80122
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Padova,Italy,35128
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Palermo,Italy,90134
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Rome,Italy,00161
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Sassari,Italy,07100
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Vicenza,Italy,36100
Study Eligibility Criteria
Additional Studies
Additional studies can be found at ClinicalTrials.gov